Endocrine Abstracts

Introduction: Acromegaly is a clinical condition results from GH hypersecretion which is usually elaborated by a somatotroph adenoma. Mass effect of adenoma and resulting hormonal changes impair fertility during pregnancy, estrogen-mediated pituitary enlargement along with enhanced pituitary vascularity is a true risk for tumor hemorrhage.Case presentation: The 28-years-old patient first visited by the endocrinologist in 2004 for secondary amenorrhea and...

Background: Spontaneous ovarian hyperstimulation syndrome (sOHSS) occurs rarely and has been associated with high level of human chorionic gonadotropin (HCG), mutated FSH receptor (FSHr) gene and hypothyroidism. We report sOHSS in two members of a family with autoimmune hypothyroidism.Patient Findings: A 15 years old girl presented with abdominal pain and distention and typical features of hypothyroidism.Serum TSH was >100 mIU/l and anti-TPO antibody...